Berberine enhances thermogenesis in brown and white adipose tissue to enhance cold tolerance. Cold proofing your body means, given adequate clothing to stop energy loss, berberine will fine tune energy metabolism to keep you comfortable even in the coldest of environments, this is in addition to keeping your heart, kidneys, digestion, and brain functioning optimally and repairing gut biome. Suggested dosage berberis vulgaris 500 mg/day, or Berberine HCL 400 mg/day, I prefer former to latter:
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better after or with dinner then! i knew this somehow (maybe from your posts on twitter or some other ..)! and it works good :)
Sounds like you have to be fat for this to work. I don't have any adipose tissue so for me staying warm in the cold means movement. More detail on whether this works for other than obese mice, please!